 | |
 Molecular structure of this compound (top), and a picture of a sample (bottom). | |
| Clinical data | |
|---|---|
| Trade names | Nipride, Nitropress, others |
| Other names | SNP |
| AHFS/Drugs.com | Monograph |
| License data |
|
| Pregnancy category |
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| Routes of administration | Intravenous |
| ATC code | |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Bioavailability | 100% (intravenous) |
| Metabolism | By haemoglobin being converted to cyanmethaemoglobin and cyanide ions |
| Onset of action | nearly immediate[3] |
| Elimination half-life | <2 minutes (3 days for thiocyanate metabolite) |
| Duration of action | 1 to 10 minutes[3] |
| Excretion | kidney (100%; as thiocyanate)[4] |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.119.126 |
| Chemical and physical data | |
| Formula | C5FeN6Na2O |
| Molar mass | 261.921 g·mol−1 |
| 3D model (JSmol) | |
| Density | 1.72 g/cm3 |
| Solubility in water | 100 mg/mL (20 °C) |
| |
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Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure.[3] This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding.[3] It is used by continuous injection into a vein.[3] Onset is nearly immediate and effects last for up to ten minutes.[3]
It is available as a generic medication.[5]
- ^ "Nitroprusside Rmb, Nitroprusside Sxp, Nitroprusside Tlb (Southern XP IP Pty Ltd)". Therapeutic Goods Administration (TGA). 5 December 2022. Retrieved 9 April 2023.
- ^ "Sodium nitroprusside Baxter (Baxter Healthcare Pty Ltd)". Therapeutic Goods Administration (TGA). 2 June 2023. Retrieved 10 September 2023.
- ^ a b c d e f "Sodium Nitroprusside". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. Retrieved 8 December 2016.
- ^ Cite error: The named reference
GGwas invoked but never defined (see the help page). - ^ "First Generic Drug Approvals". U.S. Food and Drug Administration. 17 October 2022. Retrieved 28 November 2022.