Staples Corner is a major road junction in London, United Kingdom. It is about 6.3 miles (10.1 km) north-west from Charing Cross and directly to the west of the Brent Cross crossover. It is within the Brent Cross Cricklewood new town.
It has two linked roundabouts and flyovers, which connect the A406 North Circular Road with the A5 Edgware Road and the start of the M1 motorway. Also running through Staples Corner, between the two roundabouts, is the Midland Main Line and Thameslink railway line.
Since 10th December 2023, it is served by Brent Cross West railway station.