Major cell cycle checkpoint in yeast
The Start point is a major cell cycle checkpoint in yeast, known as the restriction point in multicellular organisms.[1] The Start checkpoint ensures cell-cycle entry even if conditions later become unfavorable. The physiological factors that control passage through the Start checkpoint include external nutrient concentrations, presence of mating factor/ pheromone, forms of stress, and size control.[2]
- ^ Irvali, D; Schlottmann, FP; Muralidhara, P; Nadelson, I; Kleemann, K; Wood, NE; Doncic, A; Ewald, JC (16 January 2023). "When yeast cells change their mind: cell cycle "Start" is reversible under starvation". The EMBO Journal. 42 (2): e110321. doi:10.15252/embj.2021110321. PMC 9841329. PMID 36420556.
- ^ Morgan, David. The Cell Cycle: Principles of Cell Control. New Science Press Ltd., London, 2007; pp 196-203.