Steroidogenic acute regulatory protein

steroidogenic acute regulatory protein
Identifiers
SymbolStAR
NCBI gene6770
HGNC11359
OMIM600617
RefSeqNM_000349
UniProtP49675
Other data
LocusChr. 8 p11.2
Search for
StructuresSwiss-model
DomainsInterPro

The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ovary, Leydig cells in the testis and cell types in the adrenal cortex.