steroidogenic acute regulatory protein | |||||||
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Identifiers | |||||||
Symbol | StAR | ||||||
NCBI gene | 6770 | ||||||
HGNC | 11359 | ||||||
OMIM | 600617 | ||||||
RefSeq | NM_000349 | ||||||
UniProt | P49675 | ||||||
Other data | |||||||
Locus | Chr. 8 p11.2 | ||||||
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The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones. It is primarily present in steroid-producing cells, including theca cells and luteal cells in the ovary, Leydig cells in the testis and cell types in the adrenal cortex.