Stewie Kills Lois and Lois Kills Stewie

"Stewie Kills Lois" and "Lois Kills Stewie"
Family Guy episodes
Promotional poster of the two episodes.
Episode nos.	Season 6 Episodes 5/6
Directed by	John Holmquist ("Stewie Kills Lois") Greg Colton ("Lois Kills Stewie")
Written by	David A. Goodman ("Stewie Kills Lois") Steve Callaghan ("Lois Kills Stewie")
Production code	5ACX17/5ACX18
Original air dates	November 4, 2007 (2007-11-04) ("Stewie Kills Lois") November 11, 2007 (2007-11-11) ("Lois Kills Stewie")
Guest appearances
Patrick Stewart as Avery Bullock Paula Abdul as herself Randy Jackson as himself Simon Cowell as himself
Episode chronology
← Previous "Believe It or Not, Joe's Walking on Air" Next → "Padre de Familia"
Family Guy season 6
List of episodes

"Stewie Kills Lois" and "Lois Kills Stewie" is a two-part episode of the sixth season of the animated comedy series Family Guy, which was originally produced for the end of the fifth season. Respectively, both parts are the fourth and fifth episode of their season, and they premiered in the United States on Fox on November 4 and 11, 2007. In the former, housewife Lois receives cruise tickets as a birthday present from anthropomorphic dog Brian, and invites her husband, Peter, on the cruise with her. This upsets Stewie, and he ultimately appears to murder Lois while she is on the cruise, only to find out that she had survived the attack as the year passes. In the latter, Lois is able to expose Stewie as the villain that he is, but he soon accomplishes his dream of world domination.

"Stewie Kills Lois" was written by David A. Goodman and directed by John Holmquist, while "Lois Kills Stewie" was written by Steve Callaghan and directed by Greg Colton. Both episodes received relatively positive reviews for their combined story arc and cultural references. "Lois Kills Stewie" featured appearances by Patrick Stewart, Paula Abdul, Randy Jackson and Simon Cowell^[1] and both episodes featured cameos by various recurring voice actors for the series.