In philosophy of science, strong inference is a model of scientific inquiry that emphasizes the need for alternative hypotheses, rather than a single hypothesis to avoid confirmation bias.
The term "strong inference" was coined by John R. Platt,[1] a biophysicist at the University of Chicago. Platt notes that some fields, such as molecular biology and high-energy physics, seem to adhere strongly to strong inference, with very beneficial results for the rate of progress in those fields.