| Subfornical organ | |
|---|---|
 Medial aspect of a brain sectioned in the median sagittal plane. (Subfornical organ not labeled, but fornix and foramen of Monro are both labeled near the center.) | |
| Details | |
| Identifiers | |
| Latin | organum subfornicale |
| MeSH | D013356 |
| NeuroLex ID | nlx_anat_100314 |
| TA98 | A14.1.08.412 A14.1.09.449 |
| TA2 | 5782 |
| FMA | 75260 |
| Anatomical terms of neuroanatomy | |
The subfornical organ (SFO) is one of the circumventricular organs of the brain.[1][2] Its name comes from its location on the ventral surface of the fornix near the interventricular foramina (foramina of Monro), which interconnect the lateral ventricles and the third ventricle. Like all circumventricular organs, the subfornical organ is well-vascularized, and like all circumventricular organs except the subcommissural organ, some SFO capillaries have fenestrations, which increase capillary permeability.[1][3][4] The SFO is considered a sensory circumventricular organ because it is responsive to a wide variety of hormones and neurotransmitters, as opposed to secretory circumventricular organs, which are specialized in the release of certain substances.[1][4][5]
- ^ a b c Gross, P. M; Weindl, A (1987). "Peering through the windows of the brain (review)". Journal of Cerebral Blood Flow & Metabolism. 7 (6): 663–72. doi:10.1038/jcbfm.1987.120. PMID 2891718.
- ^ Oldfield BJ, Mckinley MJ (1995). Paxinos G (ed.). The Rat Nervous System. San Diego: Academic Press. pp. 391–403. ISBN 978-0-12-547635-5.
- ^ Sposito NM, Gross PM (1987). "Topography and morphometry of capillaries in the rat subfornical organ". J Comp Neurol. 260 (1): 36–46. doi:10.1002/cne.902600104. PMID 3597833. S2CID 26102264.
- ^ a b Miyata, S (2015). "New aspects in fenestrated capillary and tissue dynamics in the sensory circumventricular organs of adult brains". Frontiers in Neuroscience. 9: 390. doi:10.3389/fnins.2015.00390. PMC 4621430. PMID 26578857.
- ^ McKinley, Michael J.; Denton, Derek A.; Ryan, Philip J.; Yao, Song T.; Stefanidis, Aneta; Oldfield, Brian J. (14 March 2019). "From sensory circumventricular organs to cerebral cortex: Neural pathways controlling thirst and hunger". Journal of Neuroendocrinology. 31 (3): e12689. doi:10.1111/jne.12689. hdl:11343/285537. ISSN 0953-8194. PMID 30672620. S2CID 58947441.