Sulfacetamide

Sulfacetamide
Clinical data
Trade names	Bleph-10
AHFS/Drugs.com	Monograph
MedlinePlus	a601114
ATC code	D10AF06 (WHO) S01AB04 (WHO), QJ01EQ21 (WHO);
Pharmacokinetic data
Elimination half-life	7 to 12.8 hours
Identifiers
	IUPAC name N-[(4-aminophenyl)sulfonyl]acetamide;
CAS Number	144-80-9 ;
PubChem CID	5320;
DrugBank	DB00634 ;
ChemSpider	5129 ;
UNII	4965G3J0F5;
KEGG	D05947 ;
ChEMBL	ChEMBL455 ;
CompTox Dashboard (EPA)	DTXSID8026060 ;
ECHA InfoCard	100.005.128
Chemical and physical data
Formula	C8H10N2O3S
Molar mass	214.24 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	182 to 184 °C (360 to 363 °F)
	SMILES O=S(=O)(c1ccc(N)cc1)NC(=O)C;
	InChI InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11) ; Key:SKIVFJLNDNKQPD-UHFFFAOYSA-N ;
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Sulfacetamide is a sulfonamide antibiotic commonly used in the treatment of bacterial infections, particularly those affecting the eyes and skin. It functions by inhibiting the synthesis of folic acid in bacteria, which is essential for their growth and reproduction, thereby exerting a bacteriostatic effect. Available in various forms, including eye drops, topical solutions, and creams, sulfacetamide is often prescribed for conditions such as conjunctivitis, seborrheic dermatitis, and acne vulgaris. Its efficacy, coupled with a relatively low risk of side effects, makes it a widely utilized agent in both ophthalmic and dermatologic care.