Surfactant protein A2

SFTPA2
Identifiers
Aliases	SFTPA2, COLEC5, PSAP, PSP-A, PSPA, SFTP1, SFTPA2B, SP-A, SPA2, SPAII, surfactant protein A2, SP-2A, ILD2
External IDs	OMIM: 178642; MGI: 109518; HomoloGene: 121995; GeneCards: SFTPA2; OMA:SFTPA2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	79,560,407 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	40,858,409 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; visceral pleura; ; upper lobe of lung; ; right lung; ; upper lobe of left lung; ; apex of heart; ; bronchial epithelial cell; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; trachea;
	Top expressed in
	right lung lobe; ; left lung; ; left lung lobe; ; trachea; ; alveolar duct; ; sexually immature organism; ; pulmonary alveolus; ; carotid body; ; aorta; ; liver;
	More reference expression data
	n/a
Gene ontology
Molecular function	carbohydrate binding; lipopolysaccharide binding; monosaccharide binding;
Cellular component	extracellular region; clathrin-coated endocytic vesicle; collagen; lamellar granule; endoplasmic reticulum membrane; extracellular space; multivesicular body; rough endoplasmic reticulum;
Biological process	respiratory gaseous exchange by respiratory system; toll-like receptor signaling pathway; surfactant homeostasis; positive regulation of phagocytosis; developmental process;
	Sources:Amigo / QuickGO
Orthologs
	729238
	20387
	ENSG00000185303
	ENSMUSG00000021789
	Q8IWL1
	P35242; Q9CQI1
	NM_001098668; NM_001320813; NM_001320814
	NM_023134
	NP_001092138; NP_001307742; NP_001307743
	NP_075623
	Wikidata
View/Edit Human	View/Edit Mouse

Surfactant protein A2 (SP-A2), also known as Pulmonary surfactant-associated protein A2 (PSP-A2) is a protein that in humans is encoded by the SFTPA2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185303 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021789 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SFTPA2 surfactant, pulmonary-associated protein A2".
^ Silveyra P, Floros J (December 2013). "Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2". Gene. 531 (2): 126–32. doi:10.1016/j.gene.2012.09.111. PMC 3570704. PMID 23069847.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185303 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021789 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SFTPA2 surfactant, pulmonary-associated protein A2".

[pmid23069847-6] Silveyra P, Floros J (December 2013). "Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2". Gene. 531 (2): 126–32. doi:10.1016/j.gene.2012.09.111. PMC 3570704. PMID 23069847.

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