Synthetic immunology

Synthetic immunology is the rational design and construction of synthetic systems that perform complex immunological functions.[1] Functions include using specific cell markers to target cells for destruction and or interfering with immune reactions.[2] US Food and Drug Administration (FDA)-approved immune system modulators include anti-inflammatory and immunosuppressive agents, vaccines, therapeutic antibodies and Toll-like receptor (TLR) agonists.[1]

  1. ^ a b Spiegel, David A. (2010-12-01). "Grand Challenge Commentary: Synthetic immunology to engineer human immunity". Nature Chemical Biology. 6 (12): 871–872. doi:10.1038/nchembio.477. ISSN 1552-4450. PMID 21079593.
  2. ^ Geering, Barbara; Fussenegger, Martin (2015-02-01). "Synthetic immunology: modulating the human immune system". Trends in Biotechnology. 33 (2): 65–79. doi:10.1016/j.tibtech.2014.10.006. ISSN 0167-7799. PMID 25466879.