Systemic vasculitis

Systemic vasculitis
Other namesNecrotizing vasculitis
A case of vasculitis on legs
SpecialtyImmunology, rheumatology

Necrotizing vasculitis, also called systemic necrotizing vasculitis,[1] is a general term for the inflammation of veins and arteries that develops into necrosis and narrows the vessels.[2]

Tumors, medications, allergic reactions, and infectious organisms are some of the recognized triggers for these conditions, even though the precise cause of many of them is unknown. Immune complex disease, anti-neutrophil cytoplasmic antibodies, anti-endothelial cell antibodies, and cell-mediated immunity are examples of pathogenetic factors.[2]

Numerous secondary symptoms of vasculitis can occur, such as thrombosis, aneurysm formation, bleeding, occlusion of an artery, loss of weight, exhaustion, depression, fever, and widespread pain that worsens in the morning.[2]

Systemic vasculitides are categorized as small, medium, large, or variable based on the diameter of the vessel they primarily affect.[3]

  1. ^ Cruz BA, Ramanoelina J, Mahr A, et al. (October 2003). "Prognosis and outcome of 26 patients with systemic necrotizing vasculitis admitted to the intensive care unit". Rheumatology. 42 (10): 1183–8. doi:10.1093/rheumatology/keg322. PMID 12777637.
  2. ^ a b c Vashi, Falguni (2014). "Vascular System and Hematology". Acute Care Handbook for Physical Therapists. Elsevier. pp. 161–199. doi:10.1016/b978-1-4557-2896-1.00007-x. ISBN 978-1-4557-2896-1.
  3. ^ Cite error: The named reference Pathophysiology and therapy of systemic vasculitides was invoked but never defined (see the help page).