The Systems Biology Graphical Notation (SBGN) is a standard graphical representation intended to foster the efficient storage, exchange and reuse of information about signaling pathways, metabolic networks, and gene regulatory networks amongst communities of biochemists, biologists, and theoreticians. The system was created over several years by a community of biochemists, modelers and computer scientists.[1]
SBGN is made up of three orthogonal languages for representing different views of biological systems: Process Descriptions, Entity Relationships and Activity Flows. Each language defines a comprehensive set of symbols with precise semantics, together with detailed syntactic rules regarding the construction and interpretation of maps. Using these three notations, a life scientist can represent in an unambiguous way networks of interactions (for example biochemical interactions). These notations make use of an idea and symbols similar to that used by electrical and other engineers and known as the block diagram. The simplicity of SBGN syntax and semantics makes SBGN maps suitable for use at the high school level.[citation needed]
Some software support for SBGN is already available, mostly for the Process Description language.[2] SBGN visualizations can be exchanged with the XML-based file format SBGN-ML.[3]
- ^ Le Novère N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, et al. (2009). "The Systems Biology Graphical Notation". Nat Biotechnol. 27 (8): 735–41. doi:10.1038/nbt.1558. PMID 19668183.
- ^ "Community#SBGN_Software". sbgn.org. Archived from the original on 2012-05-07. Retrieved 2009-11-30.
- ^ "Systems Biology Graphical Notation". Systems Biology Graphical Notation. Retrieved 2020-08-11.