T7 phage

"Gp5" redirects here. For other uses, see GP5.
Bacteriophage T7 Structural Model at Atomic Resolution[1]
Escherichia virus T7
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Uroviricota
Class: Caudoviricetes
Order: Caudovirales
Family: Autographiviridae
Genus: Teseptimavirus
Species:
Escherichia virus T7

Bacteriophage T7 (or the T7 phage) is a bacteriophage, a virus that infects bacteria. It infects most strains of Escherichia coli and relies on these hosts to propagate. Bacteriophage T7 has a lytic life cycle, meaning that it destroys the cell it infects. It also possesses several properties that make it an ideal phage for experimentation: its purification and concentration have produced consistent values in chemical analyses;[2] it can be rendered noninfectious by exposure to UV light;[3] and it can be used in phage display to clone RNA binding proteins.[3]

  1. ^ Padilla-Sanchez, Victor (2021-07-10), Bacteriophage T7 Structural Model at Atomic Resolution, doi:10.5281/zenodo.5133295, retrieved 2021-07-24
  2. ^ Studier, F. William (1969-11-01). "The genetics and physiology of bacteriophage T7". Virology. 39 (3): 562–574. doi:10.1016/0042-6822(69)90104-4. ISSN 0042-6822. PMID 4902069.
  3. ^ a b Teesalu, Tambet; Sugahara, Kazuki N.; Ruoslahti, Erkki (1 January 2012). "Mapping of Vascular ZIP Codes by Phage Display". In Wittrup, K. Dane; Verdine, Gregory L. (eds.). Methods in Enzymology. Vol. 503. Academic Press. pp. 35–56. doi:10.1016/B978-0-12-396962-0.00002-1. ISBN 978-0-12-396962-0. PMID 22230564.