TAC3

TAC3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P9F
Identifiers
Aliases	TAC3, HH10, NKB, NKNB, PRO1155, ZNEUROK1, tachykinin 3, tachykinin precursor 3, NK3, LncZBTB39
External IDs	OMIM: 162330; MGI: 98476; HomoloGene: 7560; GeneCards: TAC3; OMA:TAC3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	57,028,883 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	127,567,637 bp
RNA expression pattern
	Top expressed in
	decidua; ; gonad; ; anterior cingulate cortex; ; caudate nucleus; ; prefrontal cortex; ; nucleus accumbens; ; dorsolateral prefrontal cortex; ; right frontal lobe; ; putamen; ; testicle;
	Top expressed in
	gastrula; ; habenula; ; lumbar subsegment of spinal cord; ; lateral hypothalamus; ; zygote; ; neural layer of retina; ; arcuate nucleus; ; nucleus of stria terminalis; ; secondary oocyte; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; protein binding; neuromedin K receptor binding; substance K receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	female pregnancy; neuropeptide signaling pathway; tachykinin receptor signaling pathway; positive regulation of flagellated sperm motility; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6866
	21334
	ENSG00000166863
	ENSMUSG00000025400
	Q9UHF0
	P55099
	NM_001006667; NM_001178054; NM_013251
	NM_001199971; NM_009312
	NP_001171525; NP_037383
	NP_001186900; NP_033338
	Wikidata
View/Edit Human	View/Edit Mouse

Tachykinin-3 is a protein that in humans is encoded by the TAC3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166863 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025400 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bonner TI, Affolter HU, Young AC, Young WS (Jan 1988). "A cDNA encoding the precursor of the rat neuropeptide, neurokinin B". Brain Res. 388 (3): 243–9. doi:10.1016/0169-328x(87)90031-3. PMID 3479225.
^ Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ (Jul 2000). "Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia". Nature. 405 (6788): 797–800. Bibcode:2000Natur.405..797P. doi:10.1038/35015579. PMID 10866201. S2CID 4392048.
^ "Entrez Gene: TAC3 tachykinin 3 (neuromedin K, neurokinin beta)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166863 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025400 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid3479225-5] Bonner TI, Affolter HU, Young AC, Young WS (Jan 1988). "A cDNA encoding the precursor of the rat neuropeptide, neurokinin B". Brain Res. 388 (3): 243–9. doi:10.1016/0169-328x(87)90031-3. PMID 3479225.

[pmid10866201-6] Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ (Jul 2000). "Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia". Nature. 405 (6788): 797–800. Bibcode:2000Natur.405..797P. doi:10.1038/35015579. PMID 10866201. S2CID 4392048.

[entrez-7] "Entrez Gene: TAC3 tachykinin 3 (neuromedin K, neurokinin beta)".

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