TFEC

TFEC
Identifiers
Aliases	TFEC, TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L, transcription factor EC
External IDs	OMIM: 604732; MGI: 1333760; HomoloGene: 32148; GeneCards: TFEC; OMA:TFEC - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	116,159,896 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	16,898,440 bp
RNA expression pattern
	Top expressed in
	monocyte; ; testicle; ; granulocyte; ; appendix; ; kidney tubule; ; bone marrow cells; ; spleen; ; lymph node; ; jejunal mucosa; ; upper lobe of left lung;
	Top expressed in
	epithelium of small intestine; ; migratory enteric neural crest cell; ; proximal tubule; ; stroma of bone marrow; ; right kidney; ; human kidney; ; yolk sac; ; morula; ; efferent ductule; ; granulocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; transcription coactivator activity; protein binding; protein dimerization activity; transcription corepressor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm;
Biological process	cellular response to heat; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of nucleic acid-templated transcription; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	22797
	21426
	ENSG00000105967
	ENSMUSG00000029553
	O14948
	Q9WTW4
	NM_001018058; NM_001244583; NM_012252
	NM_031198
	NP_001018068; NP_001231512; NP_036384
	NP_112475
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor EC is a protein that in humans is encoded by the TFEC gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105967 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029553 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yasumoto K, Shibahara S (Aug 1997). "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator". Biochim Biophys Acta. 1353 (1): 23–31. doi:10.1016/s0167-4781(97)00034-1. PMID 9256061.
^ "Entrez Gene: TFEC transcription factor EC".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105967 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029553 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9256061-5] Yasumoto K, Shibahara S (Aug 1997). "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator". Biochim Biophys Acta. 1353 (1): 23–31. doi:10.1016/s0167-4781(97)00034-1. PMID 9256061.

[entrez-6] "Entrez Gene: TFEC transcription factor EC".

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