TMEM128

TMEM128
Identifiers
Aliases	TMEM128, transmembrane protein 128
External IDs	MGI: 1913559; HomoloGene: 11944; GeneCards: TMEM128; OMA:TMEM128 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	4,248,223 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	38,426,978 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; skin of arm; ; C1 segment; ; palpebral conjunctiva; ; seminal vesicula; ; pancreatic epithelial cell; ; hypothalamus; ; synovial joint; ; corpus epididymis;
	Top expressed in
	spermatocyte; ; medullary collecting duct; ; renal corpuscle; ; facial motor nucleus; ; endocardial cushion; ; medial ganglionic eminence; ; epithelium of lens; ; right kidney; ; endothelial cell of lymphatic vessel; ; superior cervical ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	integral component of membrane; membrane; cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	85013
	66309
	ENSG00000132406
	ENSMUSG00000067365
	Q5BJH2
	Q9CZB9
	NM_001297551; NM_001297552; NM_032927
	NM_025480; NM_001356960
	NP_001284480; NP_001284481; NP_116316
	NP_079756; NP_001343889
	Wikidata
View/Edit Human	View/Edit Mouse

TMEM128, also known as Transmembrane Protein 128, is a protein that in humans is encoded by the TMEM128 gene. TMEM128 has three variants, varying in 5' UTR's and start codon location.^[5] TMEM128 contains four transmembrane domains and is localized in the Endoplasmic Reticulum membrane.^[6]^[7]^[8] TMEM128 contains a variety of regulation at the gene, transcript, and protein level. While the function of TMEM128 is poorly understood, it interacts with several proteins associated with the cell cycle, signal transduction, and memory.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132406 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000067365 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Transmembrane Protein 128, transcript variant 1, mRNA". NCBI. March 1, 2020.
^ Cite error: The named reference :3 was invoked but never defined (see the help page).
^ Gutzmann J (2013). "Characterization of Tmem128 – An activity regulated ER protein, interacting with the immediate early gene Arc/Arg3.1". Refubium. doi:10.17169/refubium-14701.
^ "PSORT II Prediction". psort.hgc.jp. Retrieved May 1, 2020.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132406 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000067365 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[:0-5] "Transmembrane Protein 128, transcript variant 1, mRNA". NCBI. March 1, 2020.

[:3-6] Cite error: The named reference :3 was invoked but never defined (see the help page).

[:12-7] Gutzmann J (2013). "Characterization of Tmem128 – An activity regulated ER protein, interacting with the immediate early gene Arc/Arg3.1". Refubium. doi:10.17169/refubium-14701.

[:7-8] "PSORT II Prediction". psort.hgc.jp. Retrieved May 1, 2020.

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