TMX1

TMX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X5E
Identifiers
Aliases	TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1
External IDs	OMIM: 610527; MGI: 1919986; HomoloGene: 12482; GeneCards: TMX1; OMA:TMX1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	51,257,655 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	70,514,814 bp
RNA expression pattern
	Top expressed in
	tibia; ; skin of hip; ; mucosa of sigmoid colon; ; germinal epithelium; ; trabecular bone; ; oral cavity; ; skin of thigh; ; jejunal mucosa; ; superficial temporal artery; ; secondary oocyte;
	Top expressed in
	retinal pigment epithelium; ; cumulus cell; ; ciliary body; ; epithelium of lens; ; Paneth cell; ; fossa; ; condyle; ; Epithelium of choroid plexus; ; aortic valve; ; supraoptic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	disulfide oxidoreductase activity; protein disulfide isomerase activity;
Cellular component	integral component of membrane; membrane; endoplasmic reticulum membrane; endoplasmic reticulum;
Biological process	protein folding; response to endoplasmic reticulum stress; cell redox homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	81542
	72736
	ENSG00000139921
	ENSMUSG00000021072
	Q9H3N1
	Q8VBT0
	NM_030755
	NM_028339
	NP_110382
	NP_082615
	Wikidata
View/Edit Human	View/Edit Mouse

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000139921 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021072 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi:10.1074/jbc.M011037200. PMID 11152479.
^ "Entrez Gene: TXNDC1 thioredoxin domain containing 1".