TNFSF12

TNFSF12
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTNFSF12, APO3L, DR3LG, TWEAK, TNLG4A, tumor necrosis factor superfamily member 12, TNF superfamily member 12
External IDsOMIM: 602695; MGI: 1196259; HomoloGene: 7979; GeneCards: TNFSF12; OMA:TNFSF12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003809

NM_011614

RefSeq (protein)

NP_003800

NP_035744

Location (UCSC)Chr 17: 7.55 – 7.56 MbChr 11: 69.58 – 69.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene.[5][6][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000239697Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000097328Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, Garcia I, Browning JL (December 1997). "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis". The Journal of Biological Chemistry. 272 (51): 32401–10. doi:10.1074/jbc.272.51.32401. PMID 9405449.
  6. ^ Marsters SA, Sheridan JP, Pitti RM, Brush J, Goddard A, Ashkenazi A (April 1998). "Identification of a ligand for the death-domain-containing receptor Apo3". Current Biology. 8 (9): 525–8. Bibcode:1998CBio....8..525M. doi:10.1016/S0960-9822(98)70204-0. PMID 9560343. S2CID 14953579.
  7. ^ "Entrez Gene: TNFSF12 tumor necrosis factor (ligand) superfamily, member 12".