TP53BP1

TP53BP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTP53BP1, 53BP1, p202, p53BP1, TP53, TDRD30, tumor protein p53 binding protein 1
External IDsOMIM: 605230; MGI: 1351320; HomoloGene: 4137; GeneCards: TP53BP1; OMA:TP53BP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001141979
NM_001141980
NM_005657
NM_001355001

NM_001290830
NM_013735

RefSeq (protein)

NP_001135451
NP_001135452
NP_005648
NP_001341930

NP_001277759
NP_038763

Location (UCSC)Chr 15: 43.4 – 43.51 MbChr 2: 121.02 – 121.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene.[5][6][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000067369Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043909Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Iwabuchi K, Bartel PL, Li B, Marraccino R, Fields S (Jun 1994). "Two cellular proteins that bind to wild-type but not mutant p53". Proceedings of the National Academy of Sciences of the United States of America. 91 (13): 6098–102. Bibcode:1994PNAS...91.6098I. doi:10.1073/pnas.91.13.6098. PMC 44145. PMID 8016121.
  6. ^ Iwabuchi K, Li B, Massa HF, Trask BJ, Date T, Fields S (Oct 1998). "Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2". The Journal of Biological Chemistry. 273 (40): 26061–8. doi:10.1074/jbc.273.40.26061. PMID 9748285.
  7. ^ "Entrez Gene: TP53BP1 tumor protein p53 binding protein 1".