TRAF5

TRAF5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4GJH
Identifiers
Aliases	TRAF5, MGC:39780, RNF84, TNF receptor associated factor 5
External IDs	OMIM: 602356; MGI: 107548; HomoloGene: 27079; GeneCards: TRAF5; OMA:TRAF5 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	211,374,946 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	191,776,868 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; body of pancreas; ; superficial temporal artery; ; lymph node; ; gastric mucosa; ; ascending aorta; ; right coronary artery; ; left uterine tube; ; Descending thoracic aorta; ; Epithelium of choroid plexus;
	Top expressed in
	spleen; ; urinary bladder; ; neural layer of retina; ; bone marrow; ; granulocyte; ; proximal tubule; ; lung; ; esophagus; ; islet of Langerhans; ; zone of skin;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	thioesterase binding; zinc ion binding; protein binding; ubiquitin protein ligase binding; metal ion binding; identical protein binding; tumor necrosis factor receptor binding;
Cellular component	cytosol; cytoplasmic side of plasma membrane; centrosome; CD40 receptor complex; cytoplasm; protein-containing complex;
Biological process	regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of DNA-binding transcription factor activity; positive regulation of NF-kappaB transcription factor activity; signal transduction; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	7188
	22033
	ENSG00000082512
	ENSMUSG00000026637
	O00463
	P70191
	NM_001033910; NM_004619; NM_145759; NM_001319207
	NM_011633
	NP_001029082; NP_001306136; NP_004610; NP_665702
	NP_035763
	Wikidata
View/Edit Human	View/Edit Mouse

TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000082512 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026637 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tang XX, Pleasure DE, Ikegaki N (Apr 1997). "cDNA cloning, chromosomal localization, and expression pattern of EPLG8, a new member of the EPLG gene family encoding ligands of EPH-related protein-tyrosine kinase receptors". Genomics. 41 (1): 17–24. doi:10.1006/geno.1997.4615. PMID 9126477.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000082512 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026637 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9126477-5] Tang XX, Pleasure DE, Ikegaki N (Apr 1997). "cDNA cloning, chromosomal localization, and expression pattern of EPLG8, a new member of the EPLG gene family encoding ligands of EPH-related protein-tyrosine kinase receptors". Genomics. 41 (1): 17–24. doi:10.1006/geno.1997.4615. PMID 9126477.

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