TSHB

TSHB
Identifiers
Aliases	TSHB, TSH-B, TSH-BETA, thyroid stimulating hormone beta, Thyroid stimulating hormone, beta, thyroid stimulating hormone subunit beta
External IDs	OMIM: 188540; MGI: 98848; HomoloGene: 463; GeneCards: TSHB; OMA:TSHB - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	115,034,302 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	102,690,034 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; testicle; ; buccal mucosa cell; ; tibialis anterior muscle; ; tibial arteries; ; gastric mucosa; ; islet of Langerhans; ; Descending thoracic aorta; ; body of uterus; ; Achilles tendon;
	Top expressed in
	pituitary gland; ; median eminence; ; anterior pituitary; ; arcuate nucleus; ; left lung lobe; ; embryo; ; pars tuberalis; ; granulocyte; ; pars distalis of adenohypophysis; ; ascending aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	hormone activity;
Cellular component	extracellular region; extracellular space; cytoplasm;
Biological process	response to calcium ion; cell-cell signaling; anatomical structure morphogenesis; G protein-coupled receptor signaling pathway; response to vitamin A; peptide hormone processing; response to estrogen; hormone-mediated signaling pathway; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	7252
	22094
	ENSG00000134200
	ENSMUSG00000027857
	P01222
	P12656
	NM_000549; NM_001277991
	NM_001165939; NM_001165940; NM_009432
	NP_000540; NP_001264920
	NP_001159411; NP_001159412; NP_033458
	Wikidata
View/Edit Human	View/Edit Mouse

Thyroid stimulating hormone, beta also known as TSHB is a protein which in humans is encoded by the TSHB gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134200 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027857 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wondisford FE, Radovick S, Moates JM, Usala SJ, Weintraub BD (September 1988). "Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species". J. Biol. Chem. 263 (25): 12538–42. doi:10.1016/S0021-9258(18)37788-3. PMID 2457586.
^ Tatsumi K, Hayashizaki Y, Hiraoka Y, Miyai K, Matsubara K (December 1988). "The structure of the human thyrotropin beta-subunit gene". Gene. 73 (2): 489–97. doi:10.1016/0378-1119(88)90513-6. PMID 3243440.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000134200 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027857 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2457586-5] Wondisford FE, Radovick S, Moates JM, Usala SJ, Weintraub BD (September 1988). "Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species". J. Biol. Chem. 263 (25): 12538–42. doi:10.1016/S0021-9258(18)37788-3. PMID 2457586.

[pmid3243440-6] Tatsumi K, Hayashizaki Y, Hiraoka Y, Miyai K, Matsubara K (December 1988). "The structure of the human thyrotropin beta-subunit gene". Gene. 73 (2): 489–97. doi:10.1016/0378-1119(88)90513-6. PMID 3243440.

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