Tachykinin receptor 2

TACR2
Identifiers
Aliases	TACR2, NK2R, NKNAR, SKR, TAC2R, Tachykinin receptor 2
External IDs	OMIM: 162321; MGI: 98477; HomoloGene: 55548; GeneCards: TACR2; OMA:TACR2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	69,416,918 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	62,101,769 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; muscle layer of sigmoid colon; ; smooth muscle tissue; ; left uterine tube; ; epithelium of colon; ; testicle; ; body of uterus; ; transverse colon; ; fundus; ; myometrium;
	Top expressed in
	adrenal gland; ; embryo; ; lumbar subsegment of spinal cord; ; right ventricle; ; stomach; ; gastrula; ; colon; ; vastus lateralis muscle; ; tibiofemoral joint; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	tachykinin receptor activity; G protein-coupled receptor activity; substance K receptor activity; signal transducer activity; protein binding;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; sperm flagellum; sperm head; sperm midpiece; plasma membrane;
Biological process	intestine smooth muscle contraction; positive regulation of acetylcholine secretion, neurotransmission; excretion; muscle contraction; negative regulation of luteinizing hormone secretion; prolactin secretion; operant conditioning; response to electrical stimulus; regulation of uterine smooth muscle contraction; positive regulation of vascular permeability; positive regulation of ion transport; positive regulation of smooth muscle contraction; signal transduction; positive regulation of uterine smooth muscle contraction; tachykinin receptor signaling pathway; chemical synaptic transmission; positive regulation of flagellated sperm motility; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6865
	21337
	ENSG00000075073
	ENSMUSG00000020081
	P21452
	P30549
	NM_001057
	NM_009314
	NP_001048
	NP_033340
	Wikidata
View/Edit Human	View/Edit Mouse

Substance-K receptor is a protein that in humans is encoded by the TACR2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000075073 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020081 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: TACR2 tachykinin receptor 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000075073 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020081 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TACR2 tachykinin receptor 2".

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