Taliesin was a 6th-century Welsh poet and bard.
Taliesin may also refer to:
- Book of Taliesin, a medieval Welsh manuscript containing poetry attributed to the bard
- Taliesin (studio), a studio of Frank Lloyd Wright in Spring Green, Wisconsin
- Taliesin Junior School, a school in Shotton, Flintshire, Wales
- Taliesin Orchestra, an orchestra that specializes in remaking famous songs into orchestral melodies
- The Book of Taliesyn, an album by Deep Purple
- Taliesin, a Fairlie locomotive owned by the Ffestiniog railway
- Taliesin, a 1987 novel in The Pendragon Cycle by Stephen R. Lawhead