Talisker is a settlement in Skye, Scotland
Talisker may also refer to:
- Talisker (band), by the Scottish percussionist Ken Hyder
- Talisker, Western Australia, in the Shire of Shark Bay#Towns and localities, Australia
- Talisker distillery, a whisky distillery near Talisker, in Carbost, Skye, Scotland
- Talisker Conservation Park, Australia
- Talisker Corporation, the owner of Main Square in Toronto