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Pharmacokinetic data | |
Bioavailability | Unknown |
Protein binding | Unknown |
Metabolism | Unknown |
Onset of action | Unknown |
Elimination half-life | Unknown |
Excretion | Unknown |
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Formula | C58H95N15O15 |
Molar mass | 1242.488 g·mol−1 |
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Teixobactin (/ˌteɪksoʊˈbæktɪn/) is a peptide-like secondary metabolite of some species of bacteria, that kills some gram-positive bacteria. It appears to belong to a new class of antibiotics, and harms bacteria by binding to lipid II and lipid III, important precursor molecules for forming the cell wall.
Teixobactin was discovered using a new method of culturing bacteria in soil, which allowed researchers to grow a previously unculturable bacterium now named Eleftheria terrae, which produces the antibiotic. Teixobactin was shown to kill Staphylococcus aureus and Mycobacterium tuberculosis.