Template:Potencies and durations of natural estrogens by intramuscular injection

Potencies and durations of natural estrogens by intramuscular injection
Estrogen Form Dose (mg) Duration by dose (mg) Refs
EPD CICD
Estradiol Aq. soln. ? – <1 d [1]
Oil soln. 40–60 – 1–2 ≈ 1–2 d [2][3]
Aq. susp. ? 3.5 0.5–2 ≈ 2–7 d; 3.5 ≈ >5 d [2][4][5][6][7]
Microsph. ? – 1 ≈ 30 d [8][9]
Estradiol benzoate Oil soln. 25–35 – 1.66 ≈ 2–3 d; 5 ≈ 3–6 d [10][11]
Aq. susp. 20 – 10 ≈ 16–21 d [12][13][14]
Emulsion ? – 10 ≈ 14–21 d [14][15]
Estradiol dipropionate Oil soln. 25–30 – 5 ≈ 5–8 d [10]
Estradiol valerate Oil soln. 20–30 5 5 ≈ 7–8 d; 10 ≈ 10–14 d;
40 ≈ 14–21 d; 100 ≈ 21–28 d		 [11][16]
Estradiol benz. butyrate Oil soln. ? 10 10 ≈ 21 d [17][18]
Estradiol cypionate Oil soln. 20–30 – 5 ≈ 11–14 d [11]
Aq. susp. ? 5 5 ≈ 14–24 d [19][20][21]
Estradiol enanthate Oil soln. ? 5–10 10 ≈ 20–30 d [22][23][24]
Estradiol dienanthate Oil soln. ? – 7.5 ≈ >40 d [25][26]
Estradiol undecylate Oil soln. ? – 10–20 ≈ 40–60 d;
25–50 ≈ 60–120 d		 [27][28]
Polyestradiol phosphate Aq. soln. 40–60 – 40 ≈ 30 d; 80 ≈ 60 d;
160 ≈ 120 d		 [29][30]
Estrone Oil soln. ? – 1–2 ≈ 2–3 d [3][31]
Aq. susp. ? – 0.1–2 ≈ 2–7 d [32]
Estriol Oil soln. ? – 1–2 ≈ 1–4 d [3][33]
Polyestriol phosphate Aq. soln. ? – 50 ≈ 30 d; 80 ≈ 60 d
Notes and sources
Notes: All aqueous suspensions are of microcrystalline particle size. Estradiol production during the menstrual cycle is 30–640 µg/d (6.4–8.6 mg total per month or cycle). The vaginal epithelium maturation dosage of estradiol benzoate or estradiol valerate has been reported as 5 to 7 mg/week. An effective ovulation-inhibiting dose of estradiol undecylate is 20–30 mg/month. Sources: Main/General: [34][35][36][37][38][39][40][41][42] Miscellaneous: [43][44][45]