The Temple of Artemis Azzanathkona was a sacred space located in block E7 at Dura Europos dedicated to a syncretic belief of Artemis and the Syrian deity named Azzanathkona. While established as a religious structure, portions of the temple were requisitioned by the Roman military after the Romans captured the city in 165 CE.
The Yale French-American excavation team began excavating the temple complex in 1931–32. Smaller subsequent excavations took place between 2007 and 2010.