Tetrandrine

Tetrandrine
Names
IUPAC name
9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24(32),25,27(31),35-dodecaene
Identifiers
3D model (JSmol)
ChEMBL
ECHA InfoCard 100.208.615 Edit this at Wikidata
KEGG
UNII
  • CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
Properties
C38H42N2O6
Molar mass 622.74988
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Tetrandrine, a bis-benzylisoquinoline alkaloid, is a calcium channel blocker.[1] It is isolated from the plant Stephania tetrandra,[2] and other Chinese and Japanese herbs.

  1. ^ Bhagya, N; Chandrashekar, KR (1 May 2016). "Tetrandrine – A molecule of wide bioactivity". Phytochemistry. 125: 5–13. Bibcode:2016PChem.125....5B. doi:10.1016/j.phytochem.2016.02.005. ISSN 0031-9422. PMID 26899361. Retrieved 24 February 2022.
  2. ^ Zhang, Lijin; Geng, Yanling; Duan, Wenjuan; Wang, Daijie; Fu, Maorun; Wang, Xiao (2009). "Ionic liquid-based ultrasound-assisted extraction of fangchinoline and tetrandrine from Stephaniae tetrandrae". Journal of Separation Science. 32 (20): 3550–3554. doi:10.1002/jssc.200900413. PMID 19764054.