| Theodora Kantakouzene | |
|---|---|
| Empress consort | |
 Empress Theodora Kantakouzene with her husband, Emperor Alexios III of Trebizond, from a chrysobull to the Dionysiou monastery, mid-14th century. | |
| Born | c. 1340 |
| Died | after 1390 |
| Spouse | Alexios III of Trebizond |
| Issue | Anna Megale Komnene, Basil Megas Komnenos, Manuel III Megas Komnenos, Eudokia Megale Komnene Maria Megale Komnene Two unnamed daughters |
| Family | Kantakouzenos |
| Dynasty | Grand Komnenos |
| Father | Nikephoros Kantakouzenos |
| Mother | unknown |
Theodora Komnene Kantakouzene (Greek: Θεοδώρα Κομνηνή Καντακουζηνή;[a] c. 1340 – after 1390) was Empress of the Empire of Trebizond as the consort of Emperor Alexios III Megas Komnenos from their marriage in 1351 until her retirement after her husband's death in 1390.
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