Thermoreceptor

Thermoreceptors of the skin sense the temperature of water

A thermoreceptor is a non-specialised sense receptor, or more accurately the receptive portion of a sensory neuron, that codes absolute and relative changes in temperature, primarily within the innocuous range. In the mammalian peripheral nervous system, warmth receptors are thought to be unmyelinated C-fibres (low conduction velocity), while those responding to cold have both C-fibers and thinly myelinated A delta fibers (faster conduction velocity).[1][2] The adequate stimulus for a warm receptor is warming, which results in an increase in their action potential discharge rate. Cooling results in a decrease in warm receptor discharge rate. For cold receptors their firing rate increases during cooling and decreases during warming. Some cold receptors also respond with a brief action potential discharge to high temperatures, i.e. typically above 45 °C, and this is known as a paradoxical response to heat [citation needed]. The mechanism responsible for this behavior has not been determined.

  1. ^ Darian-Smith I, Johnson KO, LaMotte C, Shigenaga Y, Kenins P, Champness P (1979). "Warm fibers innervating palmar and digital skin of the monkey: responses to thermal stimuli". Journal of Neurophysiology (Article). 42 (5): 1297–1315. doi:10.1152/jn.1979.42.5.1297. PMID 114608.
  2. ^ Torebjörk, ERIK; Schmelz, MARTIN (2005-01-01), Dyck, Peter J.; Thomas, P. K. (eds.), "Chapter 38 - Single-Unit Recordings of Afferent Human Peripheral Nerves by Microneurography", Peripheral Neuropathy (Fourth Edition), Philadelphia: W.B. Saunders, pp. 1003–1014, ISBN 978-0-7216-9491-7, retrieved 2023-06-21