Thermus thermophilus

Thermus thermophilus
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Deinococcota
Class: Deinococci
Order: Thermales
Family: Thermaceae
Genus: Thermus
Species:
T. thermophilus
Binomial name
Thermus thermophilus
(ex Oshima and Imahori 1974) Manaia et al. 1995

Thermus thermophilus is a Gram-negative bacterium used in a range of biotechnological applications, including as a model organism for genetic manipulation, structural genomics, and systems biology. The bacterium is extremely thermophilic, with an optimal growth temperature of about 65 °C (149 °F). Thermus thermophilus was originally isolated from a thermal vent within a hot spring in Izu, Japan by Tairo Oshima and Kazutomo Imahori.[1] The organism has also been found to be important in the degradation of organic materials in the thermogenic phase of composting.[2] T. thermophilus is classified into several strains, of which HB8 and HB27 are the most commonly used in laboratory environments. Genome analyses of these strains were independently completed in 2004.[3] Thermus also displays the highest frequencies of natural transformation known to date. [4]

  1. ^ Oshima T, Imahori K (January 1974). "Description of Thermus thermophilus (Yoshida and Oshima) comb. nov., a nonsporulating thermophilic bacterium from a Japanese thermal spa". International Journal of Systematic and Evolutionary Microbiology. 24 (1): 102–12. doi:10.1099/00207713-24-1-102.
  2. ^ Beffa T, Blanc M, Lyon PF, Vogt G, Marchiani M, Fischer JL, Aragno M (May 1996). "Isolation of Thermus strains from hot composts (60 to 80 °C)". Applied and Environmental Microbiology. 62 (5): 1723–7. Bibcode:1996ApEnM..62.1723B. doi:10.1128/AEM.62.5.1723-1727.1996. PMC 167946. PMID 8633870.
  3. ^ Henne A, Brüggemann H, Raasch C, Wiezer A, Hartsch T, Liesegang H, et al. (May 2004). "The genome sequence of the extreme thermophile Thermus thermophilus". Nature Biotechnology. 22 (5): 547–53. doi:10.1038/nbt956. PMID 15064768. S2CID 25469576.
  4. ^ Koyama, Y; Hoshino, T; Tomizuka, N; Furukawa, K (1986). "Genetic transformation of the extreme thermophile Thermus thermophilus and of other Thermus spp". Journal of Bacteriology. 166 (1): 338–340. doi:10.1128/jb.166.1.338-340.1986. PMC 214599. PMID 3957870.