Thioglycolic acid

Thioglycolic acid[1]
Space-filling model of thioglycolic acid
Names
Preferred IUPAC name
Sulfanylacetic acid
Other names
2-Sulfanylacetic acid
2-Mercaptoacetic acid
Acetyl mercaptan
Mercaptoacetate
Mercaptoacetic acid
Thioglycolic acid
Thiovanic acid[2]
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.616 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4) checkY
    Key: CWERGRDVMFNCDR-UHFFFAOYSA-N checkY
  • InChI=1/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)
    Key: CWERGRDVMFNCDR-UHFFFAOYAP
  • C(C(=O)O)S
Properties
C2H4O2S
Molar mass 92.11 g·mol−1
Appearance colorless, clear liquid[3]
Odor strong, disagreeable[3]
Density 1.32 g/cm3
Melting point −16 °C (3 °F; 257 K)
Boiling point 96 °C (205 °F; 369 K) at 5 mmHg
miscible[3]
Vapor pressure 10 mmHg (17.8 °C)[3]
−50.0·10−6 cm3/mol
Hazards
GHS labelling:
GHS05: Corrosive GHS06: Toxic
H301+H311+H331, H314
Flash point > 110 °C; 230 °F; 383 K[3]
Explosive limits 5.9%[3]
NIOSH (US health exposure limits):
PEL (Permissible)
 none[3]
REL (Recommended)
 TWA 1 ppm (4 mg/m3) [skin][3]
IDLH (Immediate danger)
 N.D.[3]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Thioglycolic acid (TGA) is the organic compound HSCH2CO2H. TGA is often called mercaptoacetic acid (MAA). It contains both a thiol (mercaptan) and carboxylic acid functional groups. It is a colorless liquid with a strongly unpleasant odor.[4][5] TGA is miscible with polar organic solvents.[6][7]

  1. ^ Merck Index, 11th Edition, 9265
  2. ^ NIOSH Pocket Guide to Chemical Hazards. CDC.
  3. ^ a b c d e f g h i NIOSH Pocket Guide to Chemical Hazards. "#0610". National Institute for Occupational Safety and Health (NIOSH).
  4. ^ "What exactly is Mercaptan?". Independent.co.uk. 22 January 2013. Archived from the original on 2022-05-07.
  5. ^ "Thioglycolic acid :Understanding the risk of specific chemicals of interest - PREVOR". 11 September 2014.
  6. ^ The Merck index, 14th ed.; O’Neil, Maryadele J., Ed.; Merck & Co., Inc.: Whitehouse Station, NJ, 2006; p. 9342.
  7. ^ Robert Rippel "Mercaptoacetic Acid and Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry, 2012, Wiley-VCH, Weinheim. doi:10.1002/14356007.a16_265.