A thiosemicarbazone is an organosulfur compound with the formula H2NC(S)NHN=CR2. Many variations exist, including those where some or all of the NH centers are substituted by organic groups. Thiosemicarbazones are usually produced by condensation of a thiosemicarbazide with an aldehyde or ketone:
- H2NC(S)NHNH2 + O=CR2 → H2NC(S)NHN=CR2 + H2O
In terms of their chemical structures, the CSN3 core atoms are coplanar.[1]
- ^ Wattanakanjana, Yupa; Pakawatchai, Chaveng; Saithong, Saowanit; Piboonphon, Prapaporn; Nimthong, Ruthairat (2012). "Iodido[1-(propan-2-ylidene)thiosemicarbazide-κS]bis(triphenylphosphane-κP)copper(I)". Acta Crystallographica Section E. 68 (11): m1417–m1418. doi:10.1107/S1600536812044066. PMC 3515154. PMID 23284381.