Thomas Holt may refer to:
- Thomas Holt (architect) (1578?–1624), English architect
- Thomas Holt (MP for Canterbury), England, in 1386
- Thomas Holt (Serjeant-at-Law) (1616–1686), English lawyer and politician; Member of Parliament for Abingdon
- Thomas Holt (Australian politician) (1811–1888), wool merchant, financier and politician
- Thomas Michael Holt (1831–1896), Governor of North Carolina, 1891–1893
- Thomas Holt (American architect) (1835–1889)
- Tom Holt (swimmer) (1923–2004), British swimmer
- Thomas C. Holt (born 1942), American writer and historian
- Tom Holt (born 1961), author of humorous fantasies and historical fiction