Thomas J. Kelly (scientist)

Thomas J. Kelly
Born1941[3]
NationalityAmerican
Alma materJohns Hopkins University
AwardsLouisa Gross Horwitz Prize of Columbia University[1] Alfred P. Sloan, Jr. Prize of the General Motors Cancer Research Foundation.[2]
Scientific career
FieldsMolecular biology, biochemistry
InstitutionsSloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center

Thomas J. Kelly is an American cancer researcher whose work focuses on the molecular mechanisms of DNA replication. Kelly is director of the Sloan-Kettering Institute,[4][5] the basic research arm of the Memorial Sloan-Kettering Cancer Center. He holds the Center's Benno C. Schmidt Chair of Cancer Research.

Before joining Sloan-Kettering in 2002, Kelly was professor and director of the Department of Molecular Biology[6] and Genetics at the Johns Hopkins University School of Medicine and was the founding director of the Johns Hopkins Institute for Basic Biomedical Sciences.[5][7]

Kelly pioneered the study of DNA replication in eukaryotic cells by using DNA viruses as model systems.[8] His laboratory developed the first cell-free systems for studying the biochemistry of DNA replication in human cells, enabling the identification and functional characterization of components of the human replication machinery.[9]

In recognition of this work he received the 2004 Alfred P. Sloan, Jr. Prize of the General Motors Cancer Research Foundation[10] and the 2010 Louisa Gross Horwitz Prize of Columbia University.[11][12]

  1. ^ "Louisa Gross Horwitz Prize". Columbia University Medical Center. 2010. Retrieved March 5, 2013.
  2. ^ "Thomas Kelly Wins General Motors Cancer Research Award". 2004-06-09.
  3. ^ "APS Member History".
  4. ^ "Johns Hopkins Malaria Research Institute External Advisory Board". Retrieved February 28, 2013.
  5. ^ a b "NIH Director Welcomes Five New Members to the Advisory Committee to the Director". National Institutes of Health. January 31, 2008.
  6. ^ "Awards, Appointments, Announcements". Journal of the National Cancer Institute. 94 (3): 165–166. 2002. doi:10.1093/jnci/94.3.165.
  7. ^ "Kari Evans, Mark Kelly Wedding Announcement". The New York Times. 2007-11-11.
  8. ^ Kelly, Thomas J., Brown, Grant W. (July 2000). "Regulation of Chromosome Replication". Annual Review of Biochemistry. 69: 829–880. doi:10.1146/annurev.biochem.69.1.829. PMID 10966477.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  9. ^ Kelly, Thomas J.; Stillman, Bruce (2006). "Duplication of DNA in Eukaryotic Cells" (PDF). In DePamphilis, Melvin L (ed.). DNA Replication and Human Disease. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press. pp. 1–29. ISBN 978-0-87969-766-2.
  10. ^ "2004 Alfred P. Sloan Jr. Prize of the General Motors Cancer Research Foundation". Landesbioscience.com. 1979-05-02. Retrieved 2013-04-23.
  11. ^ "Honoring Two Pioneers of Genetics and Cancer Research". Columbia University. 2011-02-28.
  12. ^ "The Louisa Gross Horwitz Prize for Biology or Biochemistry". Columbia University Medical Center. Retrieved 2013-03-05.