Thomas Mayer may refer to:
- Thomas Mayer (American economist) (1927–2015)
- Thomas Mayer (German economist) (born 1954)
- Thomas Mayer (motorcyclist), German motorcycle racer
- Thomas Mayer (footballer, born 1995), Austrian footballer
- Thomas Mayer (conductor), in Tasmanian Symphony Orchestra
- Thomas Mayer (skier), see Kevin Bramble
- Thomas Mayer (footballer, born 1927), German footballer in the 1956–57 DFB-Pokal
- Thomas Mayer (footballer, born 1984), German footballer
- Tom W. Mayer, writer and professor of English