Three strikes or 3 Strikes may refer to:
- Strikeout (or strike-out) in baseball or softball, when a batter receives three strikes during his time at bat, which leads to an "out"; a strikeout is a statistic recorded for both pitchers and batters
- Three strikes (policy), Internet disconnection for repeat offenders of copyright violations
- Three-strikes law, U.S. state laws for repeat offenders
- Three strikes (Revolutionary War), the three strikes necessary for the American Revolutionary War to start
- Turkey (bowling), in the sport of bowling, three consecutive strikes is known as a "turkey" or "triple"