Thrombospondin type 1 domain | |||||||||
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Identifiers | |||||||||
Symbol | TSP_1 | ||||||||
Pfam | PF00090 | ||||||||
InterPro | IPR000884 | ||||||||
SMART | SM00209 | ||||||||
PROSITE | PS50092 | ||||||||
SCOP2 | 1lsl / SCOPe / SUPFAM | ||||||||
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Thrombospondins (TSPs) are a family of secreted glycoproteins with antiangiogenic functions. Due to their dynamic role within the extracellular matrix they are considered matricellular proteins.[1] The first member of the family, thrombospondin 1 (THBS1), was discovered in 1971 by Nancy L. Baenziger.[2]