Timepidium bromide

Timepidium bromide
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		SC, IM, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 3-(di-2-thienylmethylene)-5-methoxy-1,1-dimethylpiperidinium bromide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H22BrNOS2
Molar mass400.39 g·mol−1
3D model (JSmol)
  • C[N+]1(CC(CC(=C(C2=CC=CS2)C3=CC=CS3)C1)OC)C.[Br-]
  • InChI=1S/C17H22NOS2.BrH/c1-18(2)11-13(10-14(12-18)19-3)17(15-6-4-8-20-15)16-7-5-9-21-16;/h4-9,14H,10-12H2,1-3H3;1H/q+1;/p-1 ☒N
  • Key:QTSXMEPZSHLZFF-UHFFFAOYSA-M ☒N
 ☒NcheckY (what is this?)  (verify)

Timepidium bromide (INN) is an anticholinergic. It is used in the symptomatic treatment of visceral spasms.[1] It is also used to relieve pain associated with various gastrointestinal disorders.[2] The quaternary nitrogen prevents it from crossing the blood brain barrier, so it is peripherally acting with no central side effects.

The same compound sans the quaternary methyl group and the methoxy ether is called tipepidine.[3]

  1. ^ "Timepidium bromide: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia". www.mims.com. Retrieved 2021-07-05.
  2. ^ "Timepidium Bromide Tablets 30mg SAWAI 100 Tablets｜Natural Pharmacy". www.mimaki-family-japan.com. Retrieved 2021-07-05.
  3. ^ Shah R, Verma PK (December 2018). "Therapeutic importance of synthetic thiophene". Chemistry Central Journal. 12 (1): 137. doi:10.1186/s13065-018-0511-5. PMC 6768136. PMID 30564984.