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| Clinical data | |
|---|---|
| Trade names | Vagistat-1, 1-Day |
| Other names | Thioconazole |
| AHFS/Drugs.com | Monograph |
| Routes of administration | Topical |
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| Identifiers | |
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| CAS Number | |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.059.958 |
| Chemical and physical data | |
| Formula | C16H13Cl3N2OS |
| Molar mass | 387.70 g·mol−1 |
| Chirality | Racemic mixture |
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Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal yeast infections.[1] They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.
Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
It was patented in 1975 and approved for medical use in 1982.[2]
- ^ Tioconazole, Mayo Clinic
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 503. ISBN 9783527607495.