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Tissue tropism is the range of cells and tissues of a host that support growth of a particular pathogen, such as a virus, bacterium or parasite.[1][2]
Some bacteria and viruses have a broad tissue tropism and can infect many types of cells and tissues.[1] Other viruses may infect primarily a single tissue.[1] For example, rabies virus affects primarily neuronal tissue. Similarly, JC virus (JCV) primarily affects and resides in kidneys.[3]
- ^ a b c McCall, LI; Siqueira-Neto, JL; McKerrow, JH (May 2016). "Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis". PLOS Pathogens. 12 (5): e1005519. doi:10.1371/journal.ppat.1005519. PMC 4881934. PMID 27227827.
- ^ Silva Pereira, Sara; Trindade, Sandra; De Niz, Mariana; Figueiredo, Luisa M. (31 May 2019). "Tissue tropism in parasitic diseases". Open Biology. 9 (5): 190036. doi:10.1098/rsob.190036. ISSN 2046-2441. PMC 6544988. PMID 31088251.
- ^ Cayres-Vallinoto IM, Vallinoto AC, Azevedo VN, Machado LF, Ishak Mde O, Ishak R (2012). "Human JCV infections as a bio-anthropological marker of the formation of Brazilian Amazonian populations". PLoS One. 7 (10): e46523–e46523. doi:10.1371/journal.pone.0046523. PMC 3470572. PMID 23071582.