Tlachene Cove (Bulgarian: залив Тлачене, ‘Zaliv Tlachene’ \'za-liv 'tla-che-ne\) is the 4 km wide cove indenting for 3.6 km Loubet Coast on the Antarctic Peninsula. It is part of Darbel Bay, entered southwest of Kudelin Point and northeast of Gostilya Point. The cove was formed as a result of the retreat of Hopkins Glacier during the last two decades of the 20th century.
The feature is named after the settlement of Tlachene in Northwestern Bulgaria.