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Tlalnelhuayocan is a municipality in the Mexican state of Veracruz, located 2 kilometres from the state capital Xalapa. It stands on the Mexico City–Veracruz railway and on Federal Highways 180 and 125. Its name was San Andrés Tlalnelhuayocan, who is the first name was used to the Nahuatl and the people of Jilotepec. Tlalnelhuayocan is formed by various localities, being, San Andres, Otilpan, Palenquillo, San Antonio, Xocotla and Xolostla the most known of them.