Toll-like receptor 1

TLR1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTLR1, CD281, TIL, TIL. LPRS5, rsc786, toll like receptor 1
External IDsOMIM: 601194; MGI: 1341295; HomoloGene: 20694; GeneCards: TLR1; OMA:TLR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003263

NM_001276445
NM_030682

RefSeq (protein)

NP_003254

NP_001263374
NP_109607

Location (UCSC)Chr 4: 38.79 – 38.86 MbChr 5: 65.08 – 65.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Toll-like receptor 1 (TLR1) is a member of Toll-like receptors (TLRs), which is a family of pattern recognition receptors (PRRs) that form the cornerstone of the innate immune system.[5][6][7] TLR1 recognizes bacterial lipoproteins and glycolipids in complex with TLR2. TLR1 is a cell surface receptor.[5] TLR1 is in humans encoded by the TLR1 gene, which is located on chromosome 4.[8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174125Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044827Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Cite error: The named reference El-Zayat_2019 was invoked but never defined (see the help page).
  6. ^ Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF (January 1998). "A family of human receptors structurally related to Drosophila Toll". Proceedings of the National Academy of Sciences of the United States of America. 95 (2): 588–593. Bibcode:1998PNAS...95..588R. doi:10.1073/pnas.95.2.588. PMC 18464. PMID 9435236.
  7. ^ Lien E, Ingalls RR (January 2002). "Toll-like receptors". Critical Care Medicine. 30 (1 Suppl): S1-11. doi:10.1097/00003246-200201001-00001. PMID 11782555.
  8. ^ "UniProt". www.uniprot.org. Retrieved 2023-06-18.