Tom Brown (chemist)

Tom Brown
Born (1952-11-10) 10 November 1952 (age 71)[5]
Barnsley, West Riding of Yorkshire, England
NationalityBritish
Alma materUniversity of Bradford
Known forDNA Repair,
Molecular genetics,
DNA Click chemistry, Primerdesign
Awards
Scientific career
FieldsChemical biology, Nanotechnology
InstitutionsUniversity of Oxford
University of Southampton
University of Edinburgh
ThesisThe chemistry of some imidazoles. (1979)
Doctoral advisorGordon Shaw
Other academic advisorsOlga Kennard OBE FRS
Websitebrowngroupnucleicacidsresearch.org.uk

Tom Brown FRSC[1] FRSE[2] (born 10 November 1952) is a British chemist, biotechnologist, and entrepreneur. He is the Professor of Nucleic acid chemistry at the Department of Chemistry[6] and Department of Oncology[7] at the University of Oxford. Currently, he is serving as the President of the Chemical Biology Interface Division of the Royal Society of Chemistry.[8] He is best known for his contribution in the field of DNA Repair,[9][10] DNA Click chemistry,[11][12][13] and in the application of Molecular genetics in forensics and diagnostics.[14][15][16]

He co-founded three biotechnology companies: Oswel Research Products, ATDBio, and Primerdesign.[17][18] As of January 2016, he is in the board of directors of last two.[19][20]

  1. ^ a b c "Interdisciplinary Award 2009 Winner". Royal Society of Chemistry. Retrieved 26 February 2016.
  2. ^ a b "RSE Fellows" (PDF). Royal Society of Edinburgh. Archived from the original (PDF) on 30 March 2016. Retrieved 26 February 2016.
  3. ^ "Royal Society of Edinburgh Directory" (PDF). Royal Society of Edinburgh. Archived from the original (PDF) on 4 March 2016. Retrieved 27 February 2016.
  4. ^ "Chemistry World Entrepreneur of the Year Award 2014 Winner". Royal Society of Chemistry. Retrieved 26 February 2016.
  5. ^ "Prof Tom Brown CChem FRSE". Debrett's People of Today. Debrett's. Retrieved 27 February 2016.
  6. ^ "Professor Tom Brown – Research Guides". Department of Chemistry, University of Oxford. University of Oxford. Retrieved 27 February 2016.
  7. ^ "Tom Brown : Department of Oncology". Department of Oncology, University of Oxford. University of Oxford. Retrieved 27 February 2016.
  8. ^ "Chemical Biology Interface Division Council". Royal Society of Chemistry. Retrieved 26 February 2016.
  9. ^ Savva, Renos (9 February 1995). "The Structural Basis of Specific Base-Excision Repair by Uracil-DNA Glycosylase". Nature. 373 (6514): 487–493. Bibcode:1995Natur.373..487S. doi:10.1038/373487a0. PMID 7845459. S2CID 4315434.
  10. ^ Leonard, GA; Thomson, J; Watson, WP; Brown, T (December 1990). "High-resolution structure of a mutagenic lesion in DNA". PNAS. 87 (24): 9573–9576. Bibcode:1990PNAS...87.9573L. doi:10.1073/pnas.87.24.9573. PMC 55214. PMID 2263612.
  11. ^ "Study shows click chemistry could provide total chemical DNA synthesis". Phys.org. 10 February 2014. Retrieved 6 March 2016.
  12. ^ El-Sagheer, Afaf H.; Brown, Tom (9 February 2010). "Click chemistry with DNA" (PDF). Chemical Society Reviews. 39 (4): 1388–1405. doi:10.1039/B901971P. PMID 20309492.
  13. ^ Thirumurugan, Prakasam; Matosiuk, Dariusz; Jozwiak, Krzysztof (27 March 2013). "Click Chemistry for Drug Development and Diverse Chemical-Biology Applications". Chemical Reviews. 113 (7): 4905–4979. doi:10.1021/cr200409f. PMID 23531040.
  14. ^ Biever, Celeste (11 January 2006). "DNA profiling moves to the scene of the crime". New Scientist. Retrieved 5 March 2016.
  15. ^ Rusling, D. A. (12 May 2005). "Four base recognition by triplex-forming oligonucleotides at physiological pH". Nucleic Acids Research. 33 (9): 3025–3032. doi:10.1093/nar/gki625. PMC 1137030. PMID 15911633.
  16. ^ Whitcombe, David; Theaker, Jane; Guy, Simon P.; Brown, Tom; Little, Steve (1999). "Detection of PCR products using self-probing amplicons and fluorescence". Nature Biotechnology. 17 (8): 804–807. doi:10.1038/11751. PMID 10429248. S2CID 2862667.
  17. ^ Houlton, Sarah (2 June 2014). "Triple-stranded success story". Chemistry World. Retrieved 27 February 2016.
  18. ^ "Tom Brown PhD, C.Chem., F.R.S.C., F.R.S.E." Bloomberg Businessweek. Bloomberg L.P. Retrieved 27 February 2016.
  19. ^ "ATDBio : About us". ATDBio. Retrieved 27 February 2016.
  20. ^ "About Primerdesign". Primerdesign. Retrieved 27 February 2016.