Toxalbumin

Toxalbumins are toxic plant proteins that disable ribosomes and thereby inhibit protein synthesis, producing severe cytotoxic effects in multiple organ systems. They are dimers held together by a disulfide bond and comprise a lectin (carbohydrate-binding protein) part which binds to the cell membrane and enables the toxin part to gain access to the cell contents. Toxalbumins are similar in structure to AB toxins found in cholera, tetanus, diphtheria, botulinum and others;[1] and their physiological and toxic properties are similar to those of viperine snake venom.[citation needed]

  1. ^ Hunter, William (1891). "On the Nature, Action, and Therapeutic Value of the Active Principles of Tuberculin". British Medical Journal. 2 (1595): 169–76. doi:10.1136/bmj.2.1595.169. JSTOR 20243302. PMC 2273336. PMID 20753375.