Transaldolase

Transaldolase
Identifiers
EC no.2.2.1.2
CAS no.9014-46-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
Transaldolase
Crystallographic structure of human transaldolase.[1][2]
Identifiers
SymbolTransaldolase
PfamPF00923
InterProIPR001585
PROSITEPDOC00741
SCOP21ucw / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1f05​, 1i2n​, 1i2o​, 1i2p​, 1i2q​, 1i2r​, 1l6w​, 1onr​, 1ucw​,1vpx​, 2cwn​
transaldolase 1
Identifiers
SymbolTALDO1
NCBI gene6888
HGNC11559
OMIM602063
RefSeqNM_006755
UniProtP37837
Other data
EC number2.2.1.2
LocusChr. 11 p15.5-15.4
Search for
StructuresSwiss-model
DomainsInterPro
transaldolase B
Identifiers
SymboltalB
NCBI gene4199095
PDB1onr
RefSeqNC_008245.1
UniProtP0A870
Other data
EC number2.2.1.2
Search for
StructuresSwiss-model
DomainsInterPro

Transaldolase is an enzyme (EC 2.2.1.2) of the non-oxidative phase of the pentose phosphate pathway. In humans, transaldolase is encoded by the TALDO1 gene.[3][4]

The following chemical reaction is catalyzed by transaldolase:

sedoheptulose 7-phosphate + glyceraldehyde 3-phosphate erythrose 4-phosphate + fructose 6-phosphate
  1. ^ Cite error: The named reference pmid10869557 was invoked but never defined (see the help page).
  2. ^ Molecular graphics images were produced using the UCSF Chimera package from the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE (October 2004). "UCSF Chimera–a visualization system for exploratory research and analysis". J Comput Chem. 25 (13): 1605–12. CiteSeerX 10.1.1.456.9442. doi:10.1002/jcc.20084. PMID 15264254. S2CID 8747218.
  3. ^ "Entrez Gene: transaldolase 1".
  4. ^ Banki K, Eddy RL, Shows TB, Halladay DL, Bullrich F, Croce CM, Jurecic V, Baldini A, Perl A (October 1997). "The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5". Genomics. 45 (1): 233–8. doi:10.1006/geno.1997.4932. PMID 9339383.