Triazenes

Dacarbazine is a triazene used in the treatment of melanoma and Hodgkin's lymphoma.[1]

Triazenes are organic compounds that contain the functional group R1−N=N−NR2R3, where the R are each any of various types of substituent groups.[2] Some anti-cancer medications and dyes are triazenes.[3] Formally, the triazenes are related to the unstable chemical triazene, H2N−N=NH.

  1. ^ "Dacarbazine". The American Society of Health-System Pharmacists. Archived from the original on 11 September 2017. Retrieved 8 December 2016.
  2. ^ Suleymanov, Abdusalom A.; Severin, Kay (2021-03-22). "Vinyl and Alkynyl Triazenes: Synthesis, Reactivity, and Applications". Angewandte Chemie International Edition. 60 (13): 6879–6889. doi:10.1002/anie.202011031. ISSN 1433-7851.
  3. ^ Berneth, Horst (2008). "Methine Dyes and Pigments". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a16_487.pub2. ISBN 978-3527306732.