Trilacoochee is an unincorporated community in the northeast corner of Pasco County, Florida, United States. It is at the northern terminus of the US 301 and US 98 multiplex. It has a non-profit "Greater Trilby Community Association" which exists to improve the life and quality of residents of the Trilby, Trilacoochee and Lacoochee area. The ZIP Code for this community is 33523, which it shares with Dade City.