Tripitramine

Not to be confused with Trimipramine or Tryptamine.
Tripitramine
Clinical data
Other namesTripitamine
Drug classMuscarinic acetylcholine receptor antagonist; Selective muscarinic acetylcholine M2 receptor antagonist
Identifiers
  • 11-[2-[6-[8-[6-[bis[2-oxo-2-(6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepin-11-yl)ethyl]amino]hexyl-methylamino]octyl-methylamino]hexylamino]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
ChEMBL
Chemical and physical data
FormulaC64H77N13O6
Molar mass1124.405 g·mol−1
3D model (JSmol)
  • CN(CCCCCCCCN(C)CCCCCCN(CC(=O)N1C2=CC=CC=C2C(=O)NC3=C1N=CC=C3)CC(=O)N4C5=CC=CC=C5C(=O)NC6=C4N=CC=C6)CCCCCCNCC(=O)N7C8=CC=CC=C8C(=O)NC9=C7N=CC=C9
  • InChI=1S/C64H77N13O6/c1-72(41-20-8-5-17-35-65-44-56(78)75-53-32-14-11-26-47(53)62(81)69-50-29-23-36-66-59(50)75)39-18-6-3-4-7-19-40-73(2)42-21-9-10-22-43-74(45-57(79)76-54-33-15-12-27-48(54)63(82)70-51-30-24-37-67-60(51)76)46-58(80)77-55-34-16-13-28-49(55)64(83)71-52-31-25-38-68-61(52)77/h11-16,23-34,36-38,65H,3-10,17-22,35,39-46H2,1-2H3,(H,69,81)(H,70,82)(H,71,83)
  • Key:YUJOQEAGGUIMED-UHFFFAOYSA-N

Tripitramine, or tripitamine, is an antimuscarinic drug which was never marketed.[1][2][3][4]

  1. ^ Melchiorre C, Antonello A, Banzi R, Bolognesi ML, Minarini A, Rosini M, et al. (March 2003). "Polymethylene tetraamine backbone as template for the development of biologically active polyamines". Medicinal Research Reviews. 23 (2): 200–233. doi:10.1002/med.10029. PMID 12500289.
  2. ^ Zlotos DP, Bender W, Holzgrabe U (1999). "Muscarinic receptor agonists and antagonists". Expert Opinion on Therapeutic Patents. 9 (8). Informa Healthcare: 1029–1053. doi:10.1517/13543776.9.8.1029. ISSN 1354-3776.
  3. ^ Eglen RM, Watson N (February 1996). "Selective muscarinic receptor agonists and antagonists". Pharmacology & Toxicology. 78 (2): 59–68. doi:10.1111/j.1600-0773.1996.tb00181.x. PMID 8822036.
  4. ^ Cite error: The named reference MelchiorreBolognesiChiarini1993 was invoked but never defined (see the help page).